Enhance Endorphin Levels


"Endorphins are chemicals, called peptides, that are made in the body. They have much of the same effect on a person as opium or morphine. As a result, they actually lower the feeling of pain in the body and can create a feeling of bliss or euphoria. They are often created and released when a person exercises; becomes excited; or even eats certain foods, such as spicy peppers or chocolate.

Not only are endorphins thought to block the sensation of pain, but they also work to lower stress levels and support the immune system. Some studies have indicated that they can cause certain cells, called natural killer cells, to be triggered. Once those cells are stimulated, they work to fight cancer cells. As a result, some researchers believe that chemicals may be used to lower the likelihood of developing cancer or to help fight the disease."

Depleted supplies of "feel good" transmitters means it will be impossible for you to feel happy, upbeat, motivated or on track. You will feel just the opposite: A decrease in energy and interest, feelings of worthlessness and a pervasive sense of helplessness to control the course of your life.

The majority of your emotions (and memories) are processed by your brain's limbic system, which includes the hypothalamus, the region that handles a range of functions from breathing and sexual satisfaction to hunger and emotional response. The limbic system is also rich with opioid receptors. When endorphins reach the opioid receptors of the highly emotional limbic system, and -- if everything is working normally -- you experience pleasure and a sense of satisfaction.

Certain transmitters, when depleted, may cause you to be easily agitated or angered, experience mild to severe anxiety and have sleep problems. You may feel more psychological and physical pain. These can all be symptoms of neurotransmitter insufficiency.
Major Neurotransmitters "Feel Good"

The use of electricity dates back in scientific history to Mesmer, who tried to use magnetism for a variety of problems. Allen Child, M.D., Assistant Professor of Pharmacy at the University of Texas at Austin, suggests that electrical therapies actually date back to ancient Egypt. Currently acceptable electrical therapies include the TENS or Transcutaneous Electrical Nerve Stimulation device, which is an acceptable treatment for pain, and variations on the TENS (FES or fine electrical stimulators ) which are used for treating some stroke patients. Electrical currents have been experimented with for hard-to-heal bone fractures. There are also now brain or cranial TENS devices (CES) which seem to impact brain chemistry in many significant ways. Cranial electrical stimulation (CES) devices are thought to raise alpha waves, raise blood levels of endorphins and increase conversion of amino acids into the brain’s neurotransmitters.

The FDA has approved CES devices for anxiety, depression, insomnia and stress.

Other possible applications of the CES are menstrual cramping, stiff neck, allergic reactions, headache, temporal lobe disorders, etc.

The bioelectrical approach may be useful to modulate neurotransmitters in the brain such that they may rebalance the immune system and help with aspects of all depression and anxiety type symptoms. Patients who first use the cranial electrical stimulation (CES) device can often experience benefit in the first 30 minute session. Often a good marker of its benefits is that it will produce good relaxation and even improve sleep. For other individuals an appropriate trial may be concurrent use with amino acids or antidepressants, which require at least three weeks to reach their full effect, and sometimes as much as two months to reach the full benefit.

"Endorphin deficiency is a condition that occurs when chemicals that are produced naturally by the brain, called endorphins, are not made in high enough amounts. This can be because of genetic or acquired reasons. Endorphins are used by the body as a type of mood and pain regulator, and they help people feel joy, contentment, and general well-being. A deficiency causes depression, chronic unexplained pain, and a low tolerance for pain. In many instances, low levels are misdiagnosed as depressive disorders."

Improved self-esteem is a key psychological benefit of Endorphine enhancement

HOW CAN A CES UNIT HELP ME

CES has shown benefit for a variety of other conditions. Phobias, closed head injuries, cigarette withdrawal, bronchial asthma, excess acid secretion by the stomach, bulimia, and anorexia nervosa all respond to CES. The alpha state induced by CES may also improve sports performance,plus learning memory and so much more.

Alpha Brain Waves
In general, we are accostumed to using the beta brain rythm. When we diminish the brain rythm to alpha, we put ourselves in the ideal condition to learn new information, keep fact, data, perform elaborate tasks, learn languages, analyse complex situations. Meditation, relaxation exercises, and activities that enable the sense of calm, also enable this alpha state. According to neuroscientists, analysing electroencephalograms of people submmited to tests in order to research the effect of decreasing the brain rythm, the attentive relaxation or the deep relaxation, produce signficant increases in the levels of beta-endorphin, noroepinephrine and dopamine, linked to feelings of enlarged mental clarity and formation of rememberances, and that this effect lasts for hours and even days. It is an ideal state for synthetic thought and creativity, the proper functions of the right hemisphere. As it is easy for the hemisphere to create images, to visualise, to make associations, to deal with drawings, diagrams and emotions, as well as the use of good-humour and pleasure, learning is better absorbed if these elements are added to the study methods. Source

Sugar rush

"Time and again you've experienced the intense effects that food can have on your moods. Cakes, cookies, and fudge are known as pleasure foods not only because they delight your taste buds but because they can make you feel calm and happy - at least temporarily. This sugar induced sense of euphoria comes from several chemical mechanisms in your brain. First of all, the sheer pleasure of tasting a chocolate treat or powdery donut stimulates your brain's pleasure pathways and the release of dopamine and endorphins, the chemicals that makes you feel exhilarated. You also get a quick surge of energy as the sugar hits your bloodstream. Unfortunately, that energized feeling lasts only as long as the sugar rush. Once your blood-sugar levels drop (about an hour or two later), you're left feeling drained and out of sorts.You become an addict looking for another hit."Source

 

 

can include:

• excessive sadness
• crying easily, even over small things like TV commercials
• being overly sensitive to pain, physically or emotionally
• finding it hard to get over losses
• craving chocolate, wine, marijuana, opiate drugs or other treats for pleasure and comfort

Neurotransmitter Deficiencies

IT IS CRITICAL that all of the major neurotransmitters be present daily and in sufficient amounts in order for the brain to be chemically balanced. When there are insufficient amounts of one or more of these it upsets the ratio and symptoms are experienced. eg

Neurotransmitter
Function
Drugs that Affect
Neurotransmitters
Neurotransmitter
Deficiencies Result In
Norepinephrine
Arousal, energy, drive
Cocaine, speed, caffeine, tobacco
Lack of drive, depression, lack of energy
GABA
Staying calm, relaxation, focus
Valium, alcohol, marijuana, tobacco
Free-floating anxiety, fearfulness, insecurity, can't relax or sleep, unexplained panic
Endorphins
Psychological / physical pain relief, pleasure, reward, good / loving feelings toward others
Heroin, marijuana, alcohol, sugar, tobacco
Overly sensitive, feelings of incompleteness, anhedonia (inability to experience pleasure normally), world lacks color, inability to love
Serotonin
Emotional stability, pain tolerance, self-confidence
Sugar, marijuana, ecstasy, tobacco
Depression, obsession, worry, low self-esteem, sleep problems, hunger, irritability

Depleted supplies of "feel good" transmitters means it will be impossible for you to feel happy, upbeat, motivated or on track. You will feel just the opposite: A decrease in energy and interest, feelings of worthlessness and a pervasive sense of helplessness to control the course of your life.

"Also known as endorphin deficiency disorder (EDS), a deficiency of endorphins can be difficult for medical professionals to diagnose initially until testing shows the lack of these chemicals. Many of the symptoms associated with EDS are similar to the symptoms that occur in depressive disorders, such as manic depression and bipolar disorder. Depression, chronic or intermittent, and general body aches are the two most common symptoms, and a person may also have a tendency to cry without a logical reason or feel pain more easily. EDS makes it difficult for people to be generally happy in their lives."

Certain transmitters, when depleted, may cause you to be easily agitated or angered, experience mild to severe anxiety and have sleep problems. You may feel more psychological and physical pain. These can all be symptoms of neurotransmitter insufficiency.
Major Neurotransmitters "Feel Good"

Endorphins-feel-good chemicals
Although more research needs to be done, endorphins are believed to produce four key effects on the bodymind: they enhance the immune system, they relieve pain, they reduce stress, and postpone the aging process.

"Reduce pain and anxiety and increase the feeling of well being. They stimulate the immune system, and they help you learn. They reduce appetite for drug and alcohol seeking behavior.
Consider endorphins, the chemicals that transmit information from one cell to another in the central nervous system and produce feelings of euphoria, intimacy, happiness, and overall well-being.

Dr. Reuer says "It’s the state of mind known as "flow," . When musicians, and amateur drummers, find themelves in flow, especially at a slower, steady beat, they can shift into a rhythm of deep relaxation and expanded awareness. These "altered states", she says, release the flow of endorphins—"feel-good" chemicals that can help improve, if even for a short time, your quality of life."

"Alpha rhythms tend to stimulate the release of the pleasure neurochemicals - endorphins, dopamine and norepinephrine. This is more so with the frequent use of CES Tools."

"There comes a point in every relationship when passionate love (signaled by a racing pulse, decreased appetite, etc.) starts to wane. That’s when the relationship either comes to an end or, if endorphins step in, develops into something deeper and more meaningful. When you’re with someone you love and trust, a release of endorphins makes you feel secure, compassionate, and connected. It’s what strengthens long-term relationships."Source

Aging
Endorphines can help slow the Aging process
In addition to a change in mood, some scientists say that endorphins make our immune system stronger, lower blood pressure and could even slow down our body's aging process.

Endorphins have anti-aging effect by removing Superoxide: The oxygen coming into the body from breathing can change into a Superoxide. This is one of the biggest enemies for human causing diseases and aging.

Immune function in the Elderly

Some scientists claim that Endorphins can remove this harmful Superoxide by facilitating the production of 'SOD' (Superoxide Dismutase). This is possible because the Endorphins can keep the brain cells young and healthy. SOD is the enzyme which neutralized the toxicity of the harmful Superoxide. Therefore Endorphins have anti-aging effect.

"Certain aromas can lift your mood by influencing the production of endorphins — the brain's "feel-good" chemicals. For example, the scent of vanilla helps reduce anxiety, which is often associated with depression. According to a study at the Memorial Sloan-Kettering Cancer Center, patients undergoing MRIs who breathed vanilla-scented air reported 63 percent less anxiety than those who breathed unscented air." Source

Scientists now know of at least seven chemicals in the endorphin family that have effects on memory and learning. Endorphins, according to neuroscientists, "serve as the body’s ‘natural reward system,’ providing us with a rush of pleasure whenever we learn something or act in some way that is conducive to our survival as a species." This means that new belief system designed to effect desirable behavior changes, if presented to the mind when it is flooded with endorphins, may be perceived as beneficial and adopted as such.

Memory You can improve your memory by the help of endorphins because they can keep the brain cells young and healthy. They will help you to maintain a harmonious relationship with your colleagues. You will also be able to think creatively and have more endurance
Scientists have found that the endorphins released when the brain is exposed to alpha and theta patterns enhance many mental functions. Endorphins have a powerful strengthening effect on learning and memory, for instance, and have been known to reverse amnesia. Researcher David de Weid found that rats injected with endorphins remembered things longer.
Dr. Andrew Schally, 1987 winner of the Nobel Prize for medicine, found that rats receiving injections of endorphins showed improved maze-running abilities.

Aging decreases beta-endorphin enhancement of T-cell mitogenesis in mice

The physiological result of the endorphin release mechanism is one of deep relaxation--respiration slows down, heart rate decreased, eyes dilate, blood is shunted from the extremities to the body’s core--which improves digestion and venous flow to the internal organs. Lymphatic speeds up and this increased the excretion of waste and toxins from the body.

Immune system
Endorphins enhance our immune system: When they are secreted, they activate natural killer cells (NK cells) and thereby increase our immune system. Under stress, your immunocompetence is reduced remarkably. NK cells are likely to lose their effects under stress. NK cells, which take responsibility for the immune system by killing defective cells, also have the ability to kill cancer cells.
If that were a mechanism of action, then many kinds of medical conditions should respond to CES, and research soon found that CES was effective in the treatment of addictions, (11-13) in head injury, (14) in various types of cognitive dysfunctions, (15-16) and more recently in reflex sympathetic dystrophy. (17-18) In addition, the use of CES in the treatment of many types of pain patients has been documented, (19,20) and ongoing studies are documenting the effectiveness of its use in treating patients suffering from the difficult fibromyalgia syndrome. (21-22)

Endorphin research suggest a link between our emotional state of well being and the health of our immune syst . Endorphins and other neurotransmitters that are flooded into our bloodstream during stressful, as well as good times, are often felt "physically" as we get a queasy or nervous feeling in our stomachs. That "gut feeling" most people, at one time or another have felt, is our second brain talking to us, according to Jeff Cohen, M.D., a Kaiser Permanente neurologist.

Stress
Endorphins are anti-stress hormones: The ability to cope with the stress is in proportion to the endorphins levels we have in our body. We will encounter great difficulties in removing our stress unless sufficient amounts of endorphins are released.

If you're feeling stressed, why not try some a stress reliever that also make you feel good?

82% of participants in one study suffering from an anxiety disorder reported a significant improvement in their symptoms after treatment with CES.
- Kirsch D, Gilula MF, Electromedicine: CES in the Treatment of Anxiety Disorders, Practical Pain Management, March 2007, pp 40-47.

During times of emotional stress, endorphins are released in the limbic system of the brain and produce a euphoria that lessens anxiety and melancholy (Rang et al., 1995)

 

Endorphins make us feel good. They give us a sensation of wellness and peace, helping shrink our problems to their true dimensions. They diminish our giants, creating a euphoric effect that gives us energy, enthusiasm and power to accomplish daily tasks (Pierce, et al., 1993).

 

Blood Pressure "The release of endorphins lowers the blood pressure, a major indicator in heart disease, and has even been implicated in the fight against cancer."

During stress, people who secrete endorphins have lower heart rate reactivity. Before and during recovery from stress, an endorphin producer has lower mean arterial blood pressure (McCubbin, et al., 1992). Endorphins are the body's own opiate (Terenius, 1982).

Endorphins are substances produced only by the human brain. They are important for pain control, as well as regulating blood pressure and body temperature (Andersson and Lundeberg, 1995)
. During stress, people who secrete endorphins have lower heart rate reactivity. Before and during recovery from stress, an endorphin producer has lower mean arterial blood pressure (McCubbin, et al., 1992). Endorphins are the body's own opiate (Terenius, 1982)
.

Anger
Chronic anger can have serious consequences on our health , resulting in hypertension, increased cholesterol levels, damaged or blocked arteries, aggravated heart disease, increased susceptibility to infection ( due to depressed immune system), and longer recovery time from major traumas to the body. When acted out, anger can result in physical violence inflicted on others, and when internalized inwards, anger can result in depression, and may lead to unhealthy coping mechanisms, such as alcohol or substance misuse
.

A study done in Texas reported an 83% positive response after CES treatment in patients suffering from severe aggression attacks that could not be managed by drugs. 67% of these severely aggressive patients that had been permanently institutionalised were well enough to be discharged after three months of daily CES treatment.
- Childs A, Price L, Cranial Electrotherapy Stimulation Reduces Aggression in Violent Neuropsychiatric Patients, Primary Psychiatry, 2007: 14(3), pp 50-56.

In animal studies at the University of Tennessee Medical Center, researchers used drugs to deliberately upset the homeostatic balance among the brain's neurotransmitters in canine subjects. In this way they induced Parkinson-like behavior in the dogs. Once all drugs were removed from their bloodstream, and the animals were put back on normal feeding schedules, they returned to normal behavior within 3-7 days. If CES treatment was applied at the time the drugs were removed, all animals returned to normal within 2-8 hours. The researchers concluded that CES was effective in bringing back to pre-stress homeostasis, neurotransmitters.

Depression

Endorphins play an important role in reducing depression According to the Mayo Clinic, endorphins, nature's free gift to us, is one way to alleviate depression Dr. Laskowski, with the Mayo Clinic says that, "Endorphins are the body's natural pain reliever." And while endorphins are known for their ability to reduce physical pain, sometimes as effective as a dose of morphine, many people do not realize that they also play a key role in reducing anxiety and depression too.

What's 3 times better than Prozac?

CES was found to be two times more effective in treating depression than the most effective antidepressant drugs on the market. In fact, CES treatment is 3 times as effective as fluoxetine (Prozac) in the curing of depression, compared to placebo (fake treatment).
- Gilula MF, Kirsch DF, Cranial Electrotherapy Stimulation Review: A Safer Alternative to Psychopharmaceuticals in the Treatment of Depression, J Neurotherapy, 2005: 9(2), pp 7-26.

Sleep
The increase in norepinephrine causes adrenaline to be released and the reduction of serotonin makes sleep difficult to impossible. [It is important to note that serotonin is a sleep enabling neurotransmitter, not a sleep inducing one. A lack of serotonin makes sleep very hard to achieve. Once the serotonin becomes available, the body demands the sleep it now badly needs.

As levels are restored, you notice that you sleep better, think more clearly, are slower to anger, feel more at peace and relaxed. You find you're more positive, focused and motivated. These feelings begin to replace negative thoughts, hopelessness and depression.


One study reported an average 67% effectiveness in treating sleeping disorders among 648 patients, while increasing daytime vigilance.
- Smith RB, Cranial Electrotherapy Stimulation, Oklahoma: Tate Publishing and Enterprises, LLC. 2007, pp 37-43.

Yawning
" The more of these compounds activated in the brain, the greater the frequency of yawns. Conversely, a greater presence in the brain of opiate neurotransmitters such as endorphins, the less the frequency of yawns."Source

The CES Can Help Stroke Victims Recover

CES is used with stroke victims. A stroke damages certain parts of the brain. The muscles have not been injured, yet, the brain can no longer send the impulses needed for movement. With a CES attached a new path to the brain is created. The old pathway was destroyed by the stroke and can not be recovered, . So, through the CES unit a new Pathway is established.

Endorphins are hundreds of times more powerful than heroin and many times more than morphine (Cornejo, 1995; Davis, 1984). In terms of stimulant power, they have a tremendous impact on attitude, the will and mental insight. Experimental work with animals has shown improvements in memory and learning capacity when endorphins were involved (Davis, 1984).

Can CES help Drug Dependence

The ability to improve anxiety, depression and insomnia has made CES a powerful adjunct for a variety of disorders, including drug and alcohol rehabilitation. CES helps reduce withdrawal symptoms regardless of the involved substance. CES has been studied with people recovering from addictions to alcohol, heroin, cocaine, marijuana, morphine and barbiturates. Studies have found CES to produce many beneficial psychological changes in recovering addicts, including: reduced anxiety, hostility and depression, improved planning, self esteem, assertiveness, decision-making skills, feeling expression, energy levels and capacity for intimate contact. CES speeds time to fall asleep, increases time spent in deepest sleep and amount of time in bed spent asleep. It also reduces confusion and bewilderment and increases IQ in recovering addicts. All of these beneficial effects add up to a fifty % reduction in recidivism (over two years of study) for substance abusers!

Memory and Learning
" Imagine how your life and career would improve if you could learn faster and retain much more without constant revisions ?" Research shows that the key to speed learning is your state of mind before, during and immediately after your learning session. It is when you are in a state of relaxed alertness that you will achieve the greatest improvement in memory together with increased concentration and creativity.
You Can Improve memory and retention of study material Enhance understanding during learning sessions
Accelerate new language learning Increase maths ability
A 386% increase in attention span test results after just 20 minutes of a single CES treatment in healthy volunteers - Southworth S, A Study of the Effects of Cranial Electrical Stimulation on Attention and Concentration, Integrative Physiological and Behavioral Science, 1999, Vol 34:1, 43-53.

Would you like to be able to feel good, or relieve pain at any time - without taking harmful drugs? Well you can, thanks to the ability of your own brain to produce endorphins.

Pain "The brain responds to pain signals by producing and activating morphine-like hormones called endorphins. This pain relief effect lasts for about 30 hours (longer than known analgesics), and without side effects when used frequently."

Sustained stimulation at low levels of pulse intensity has a strong effect on managing chronic nagging pain. Experience has shown that for the management of chronic pain, an endorphin release is by far the most effective application of CES.. Endorphins flow through the circulatory system acting like pain medication, inhibiting pain message transmission at nerve junctions throughout the body.

For the past two years a “slipped disk” has kept me from exercising, and in varying degrees of pain. I consulted an orthopedic surgeon, and after reading my MRI, he called me and asked how I was managing to walk around. I have used TENS machines to lessen the pain, and the back pain and sciatica have ranged from moderate to horrible. I have been a dentist for over thirty-five years, and back problCES are endemic within the profession. At age 61, I was feeling like an old guy.More

 

 

If you are using a Medical protocol

CES can be used in conjunction with medication, psychotherapy, biofeedback and other therapies. It often augments the effects of other treatments. CES helps prevent rebound depression in patients being weaned off anti–anxiety medication. While medication may be effective in treating symptoms of anxiety or depression, it interferes with the re-establishment of homeostasis in the brain. In contrast, CES does restore balance to the brain.

CES is also very effective for pain relief. In addition to the arthritis study previously cited, headaches, fibromyalgia, low back pain, reflex sympathetic dystrophy, and Temporomandibular joint (TMJ) dysfunction syndrome are a few of the chronic pain states documented to respond to CES.

CES has been found to reduce frequency, intensity and duration of migraine headaches. Fibromyalgia patients with severe chronic headaches were treated with CES. These patients had failed to respond to various medications, biofeedback, low tyramine diet, physical therapy and local injections. About half of the seventy-five subjects had a significant reduction in the frequency and intensity of headaches. This study also found an overall net decrease in the sensitivity of six main tender points on various parts of the body

Is CES safe?
CES has an unblemished safety record. A broad reading of published literature on the subject shows no negative effects or major contraindications from its use, either in the U.S. or in other parts of the world. The National Research Council has deemed CES a non-significant risk modality.
The unit's sole source of current are common 1.5 - 9 volt batterys. Its intensity is limited —no more than is required to run a small toy or a penlight. Even when turned to maximum intensity, it is not harmful. It is suggested, however, that until you become fully acclimated to your unit, you maintain the intensity at a lower setting

CES effects are long lasting and cumulative

The efficacy of CES has been demonstrated in many different ways. Studies have used twenty-seven different psychometric (pencil and paper) tests including the Minnesota Multiphasic Personality Inventory and the State/Trait Anxiety Inventory. CES has consistently demonstrated reductions in anxiety on these tests. Other studies have measured the physiological manifestations of anxiety before and after CES treatment. Slowing of brain waves and respiration rate, as well as reduction in blood pressure are physical signs of stress reduction that have been documented with CES treatment. One placebo-controlled study evaluated the effects of CES treatment in twenty individuals with chronic stress symptoms of at least a year’s duration. All of them had failed to respond to medication. Muscle tension, heart rate and finger temperature were measured before, immediately after, and one week following a single twenty minute CES treatment. Muscle tension and heart rate decreased and finger temperature increased immediately after treatment in those receiving active CES treatment but not in the placebo (sham CES) group. One week after treatment, those who had received active CES treatment still had significantly reduced muscle tension and heart rate! This is one of the many advantages of CES over medications. Whereas medications only work as long as they are taken, .

Homeostasis can be defined as the tendency for intrinsic balance within a system. Application of a range of CES appears to enhance the Balance of the biological central nervous system. A change in one system within the individual will have correlative effects upon other systCES. Improvements in mood, cognitive function, self image, shift of locus , control to oneself, and sense of well being can be measured. When CES works, it enhances one's ability to handle or deal with situations that were previously beyond the range of one's control.

Its now within your control

Research conducted throughout the 20th century has demonstrated that the brain makes use of electrical activity; thus, one can affect mental functions by affecting the organ's electrical activity.

During CES, an electric current is focused upon the hypothalamic region; during this process, CES electrodes are placed behind the ear at the mastoid, or clipped to the portion of the earlobe, near to the face. CES treatment promotes an increase in endorphins; note, scientists remain unsure why this occurs. The current results in an increase of the brain's levels of serotonin, norepinephrine, and dopamine, and a decrease in its level of cortisol. When CES is effective, users are in an "alert, yet relaxed" state, characterized by alpha brain waves.

Effectiveness
Most users report a decrease in anxiety during treatment, and many other report a decrease in anxiety as much as two days later. Some users report a euphoric feeling; they report that their bodies feel "lighter", their thinking is clearer, and that they are more creative.

A minority of users require five to ten treatments to achieve any effect.

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sources
Eric Braverman, M.D.
Dr. Joseph A. Debé
Addiction