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Stem Cell Enhancement

Stem Cell Enhancement

 

Stem cells have the remarkable potential to develop into many different cell types in the body. Serving as a sort of repair system for the body, they can theoretically divide without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential to either remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Stem cells are cells found in all multi-cellular organisms. They retain the ability to renew themselves through mitotic cell division and can differentiate into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s

Stem cell research has been hailed for the potential to revolutionize the future of medicine with the ability to regenerate damaged and diseased organs. On the other hand, stem cell research has been highly controversial due to the ethical issues concerned with the culture and use of stem cells derived from human embryos. This article presents an overview of what stem cells are, what roles they play in normal processes such as development and cancer, and how stem cells could have the potential to treat incurable diseases.

Stem cell research has been hailed for the potential to revolutionize the future of medicine with the ability to regenerate damaged and diseased organs. On the other hand, stem cell research has been highly controversial due to the ethical issues concerned with the culture and use of stem cells derived from human embryos. This article presents an overview of what stem cells are, what roles they play in normal processes such as development and cancer, and how stem cells could have the potential to treat incurable diseases.

In addition to offering unprecedented hope in treating many debilitating diseases, stem cells have advanced our understanding of basic biological processes.

Frequently Asked Questions (FAQs)


Three processes in which stem cells play a central role in an organism, development, repair of damaged tissue, and cancer resulting from stem cell division going awry.

Research and clinical applications of cultured stem cells: this includes the types of stem cells used, their characteristics, and the uses of stem cells in studying biological processes, drug development and stem cell therapy; heart disease, diabetes and Parkinson's disease are used as examples.

During development, stem cells divide and produce more specialized cells. Stem cells are also present in the adult in far lesser numbers. The role of adult stem cells (also called somatic stem cells) is believed to be replacement of damaged and injured tissue. Observed in continually-replenished cells such as blood cells and skin cells, stem cells have recently been found in other tissue, such as neural tissue.

Organ regeneration has long been believed to be through organ-specific and tissue-specific stem cells. Hematopoietic stem cells were believed to replenish blood cells, stem cells of the gut to replace cells of the gut and so on. Recently, using cell lineage tracking, stem cells from one organ have been discovered that divide to form cells of another organ. Hematopoietic stem cells can give rise to liver, brain and kidney cells. This plasticity of adult stem cells has been observed not only under experimental conditions, but also in people who have received bone marrow transplants.4

For wound healing in the skin, epidermal stem cells and bone-marrow progenitor cells both contribute.6 Thus it is likely that organ-specific progenitors and hematopoietic stem cells are involved in repair, even for other organ repair.


WELCOME TO THE WORLD OF WELLNESS AND THE MAGIC OF

StemEnhance™
“ helping your body help itself”

THE WORLD'S FIRST PRODUCT
to support the natural release of adult stem cells

 

What is a Stem Cell Enhancement?

StemEnhance is a breakthrough, natural botanical extract that supports wellness by helping your body maintain healthy stem cell physiology. It is the very first product on the market from the latest phytoceutical product category called “stem cell enhancers”.

What are stem cell enhancers?

Recent scientific developments have revealed that stem cells derived from the bone marrow, travel throughout the body, and act to support optimal organ and tissue function. Stem cell enhancers are products that support the natural role of adult stem cells.

Why do I need Stem Cell Enhancement?

As you age, the number and quality of stem cells that circulate in your body gradually decrease, leaving your body more susceptible to injury and other age-related health challenges.

Stemtech Science and your health

Just as antioxidants are important to protect your cells from “free radical” damage, stem cell enhancement is equally important to support your stem cells in maintaining proper organ and tissue functioning in your body.

How does it work?

When you take two capsules, the ingredients help to support the release of stem cells from the bone marrow into the bloodstream. Through a natural process, those stem cells then travel to areas of the body where they are most needed.

What are stem cells?

Stem cells can be thought of as “master” cells. You’ve probably heard about the controversy of embryonic stem cells in the news. Stem cells are found in human embryos, but are also found in adult tissue.

Adult stem cells are most abundantly found in bone marrow. Stem cells circulate and function to replace dysfunctional cells, thus fulfilling the natural process of maintaining optimal health.StemEnhance supports the release of adult stem cells from bone marrow into circulation.

The recent advances in stem cell research were listed as one of the most significant health-related stories in the past 25 years by CNN, second only to the complete mapping of the human genome.

Is StemEnhance scientifically studied?

Yes. Several clinical studies have been conducted on the product, in addition to several in-vitro trials.

Where is it available?

StemEnhance is only available through StemTech HealthSciences, Inc. and its independent distributors. The formulation is patented and is the first of its kind on the market.

Why the StemEnhance Product?

Effectiveness of StemEnhance was demonstrated in a triple-blind study.Volunteers rested for one hour before establishing baseline levels. After the first blood samples, volunteers were given StemEnhance™ or placebo. Thereafter, blood samples were taken at 30, 60 and 120 minutes after taking the consumables. The number of circulating stem cells was quantified by analyzing the blood samples using Fluorescence-Activated Cell Sorting (FACS). Consumption of StemEnhance™ triggered a significant 25-30% increase in the number of circulating stem cells.

Few quarrel with predictions of the awesome potential that stem cell research holds. One day, scientists say, stem cells may be used to replace or repair damaged cells, and have the potential to drastically change the treatment of conditions like cancer, Alzheimer's and Parkinson's disease and even paralysis.

 

For ethical issues and stem cell research refer to http://stemcells.nih.gov/info/ethics.asp; Ethical Issues Associated with Pluripotent Stem Cells. Human Embryonic Stem Cells (2003) ed. by Chiu A.Y., Rao, M.S, 3-25.
Sell, S. (2004) Stem cells. Stem Cell Handbook ed. by Sell, S. 1-18.
Forbes, S.J., Vig, P., Poulsom, R., Wright, N.A., Alison, M.R. (2002) Adult Stem Cell Plasticity: New Pathways of Tissue Regeneration become Visible. Clin. Sci. 103, 355-369.
Asahara T., Isner, J.M. (2004) Endothelial Progenitor Cells. Stem Cell Handbook ed. by Sell, S. 221-227.

Lindblad, W.J. (2004) Stem cells in Dermal Wound Healing. Stem Cell Handbook ed. by Sell, S. 101-105.
McCulloch, E.A. (2004) Normal and Leukemic Hematopietic Stem cells and Lineages. Stem Cell Handbook ed. by Sell, S. 119-131.
Tsai, R.Y.L. (2004) A Molecular View of Stem Cell and Cancer Cell Self-renewal. Intl. J. Biochem. Cell Biol. 36, 684-694.
Cai, J., Weiss M.L., Rao, M.S. (2004) In Search of "stemness". Exp. Hematol. 32, 585-598.
Roach, M.L., McNeish, J.D. (2002) Methods for the Isolation and Maintenance of Murine Embryonic Stem Cells. Embryonic Stem Cells Methods and Protocols ed. by Turksen K. 1-16.
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Evans, M.J., Kaufman, M.H. (1981) Establishment in Culture of Pluripotenial Cells from Mouse Embryos. Nature 292, 154-156; Axelrod, H.R. (1984) Embryonic Stem Cell Lines Derived from Blastocysts by a Simplified Technique. Dev. Biol. 101, 225-228; Wobus, A.M., Holzhausen H., Jakel, P., Schneich, J. (1984) Characterization of a Pluripotent Stem Cell Line Derived from a Mouse Embryo. Exp. Cell Res. 152, 212-219; Doetschman, T.C. Eistattaer, H., Katz, M., Schmidt, W., and Kemler, R. (1985) The in vitro development of Blastocyst Derived Embryonic Stem Cell Lines: formation of Yolk Sac, Blood Islands and Myocardium. J. Embryol. Exp. Morphol. 87, 27-45.
Thompson, J.A., Kalishman, J., Golos, T.G., Durning, M., Harris, C.P., Becker, R.A., Hearn, J.P. (1995) Isolation of a Primate Embryonic Stem Cell Line. Proc. Natl. Acad. Sci. USA 86, 7844-7848; Thomson, J.A, Itskovitz-Eldor, J., Shapiro, S.S., Waknitz, M.A., Swiergiel, J.J., Marshal, V.S., Jones, J.M. (1998) Embryonic Stem Cell Lines Derived from Human Blastocysts. Science 282, 1145-1147.
Amit, M., Segev, H., Manor, D., Itskovitz-Eldor, J. (2003) Subcloning and Alternative Methods for the Derivation and Culture of Human Embryonic Stem Cells. Human Embyronic Stem Cells ed. by Chiu, M., Rao, M.S. 127-141.
Carpenter, M.K., Xu, C., Daigh, C.A., Antosiewicz, J.E., Thomson, J.A. (2003) Protocols for the Isolation and Maintenance of Human Embryonic Stem Cells. Human Embyronic Stem Cells ed. by Chiu, M., Rao, M.S.
Drukker M., Benvenisty, N. (2003) Genetic Manipulation of Human Embryonic Stem Cells. Human Embryonic Stem Cells ed. by Chiu, A.Y., Rao, M.S. 265-284.

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Shamblott, M.J., Axelman, J., Wang, S., Bugg, E.M., Littlefield, J.W., Donovan, P.J., Blumenthal, P.D., Huggins, G. R., Gearhart J.D., (1998) Derivation of Pluripotent Stem Cells from Cultured Human Primordial Germ CellS. Proc. Natl. Acad. Sci.USA 95, 13726-13731.
Doyonnas, R., Blau, H.M. (2004) What is the Future of Stem Cell Research? Stem Cell Handbook ed. by Sell, S. 491-499.
Draper, J.S. Moore, H., Andrews, P.W. (2003) Embryonal Carcinoma Cells. Human Embryonic Stem Cells ed. Chiu, A. Y., Rao, M.S. 63-87.
Adult Stem Cells ed. Turksen, K. (2004) Nosrat, I.V., Smith, C. A., Mullally, P., Olson, L., Nosrat C.A. (2004) Dental Pulp Cells Provide Neurotrophic Support for Dopaminergic Neurons and Differentiate into Neurons in vitro; implications for Tissue Engineering and Repair in the Nervous System. Eur. J. of Neurosci. 19, 2388-2398.
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Shen, C-N., Horb, M.E., Slack, J.M.W., Tosh,D. (2003) Transdifferentiation of Pancreas to Liver. Mech. Dev.120, 107-116.
Priller, J. (2004) From Marrow to Brain. Adult Stem Cells ed. by Turksen, K. 215-233.
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For review: Floss,T., Wurst, W. (2002) Functional Genomics by Gene-trapping in ES cells. Embryonic Stem Cells Methods and Protocols ed. by Turksen, K. 347-379.
McNeish, J. (2004) Embryonic Stem Cells in Drug Discovery Nat. Rev. Drug Discov. 3, 70-80.
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Barker, R.A., Jain, M., Armstrong, R.J.E., Caldwell, M.A. (2003) Stem Cells and Neurological Disease. J. Neurol. Neurosurg. Psychiat. 74, 553-557.
Jackson, K.A., Goodell, M.A. (2004) Generation and Stem Cell Repair of Cardiac Tissue. Stem Cell Handbook, edited by Sell, S. 259-266.
Kehat, I., Khimovich, L., Caspi, O., Gepstein, A., Shofti, R., Arbel, G., Huber, I., Satin, J., Itskovitz-Eldor, J., Gepstein, L. (2004) Electromechanical Integration of Cardiomyocytes Derived from Human Embryonic Stem Cells . Nature Biotechnol. 22, 1282-1289.
Fraser, J.K., Schreiber, R.E., Zuk, P.A., Hedrick, M.H. (2004) Adult Stem Cell Therapy for the Heart. Intl. J. Biochem. Cell Biol. 36, 658-666.
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Cohen, S., Leor, J. (2004) Rebuilding Broken Hearts. Scientific American Nov. 2004, 45-51.
Street, C.N., Sipione, S., Helms, L., Binette, T., Rajotte, R.V., Bleackley, R.C., Korbutt, G.S. (2004) Stem Cell-based Approaches to Solving the Problem of Tissue Supply for Islet Transplantation in Type I Diabetes. Intl. J. Biochem. Cell Biol. 36, 667-683.
Bouwens, L. (2004) Islet Cells. Stem Cell Handbook ed. by Sell, S. 429-438.
Seaberg, R.M., Smukler, S.R., Kieeffer, T.J., Enikolopov, G., Asghar, Z., Wheeler M.B., Korbutt, G., van der Kooy, D. (2004) Clonal Identification of Multipotent Precursors from Adult Mouse Pancreas that Generate Neural and Pancreatic Lineages. Nat. Biotechnol. 22, 1115-1124.; SeNakajima-Nagata, N., Sakurai, T., Mitaka, T., Katakai, T., Yamaot, E., Miyazaki, J., Tabata, Y., Sugai, M., Shimzu, A.. (2004) In vitro Induction of Adult Hepatic Progenitor Cells into Insulin-producing Cells. Biochem. Biophys. Res. Commun. 318, 625-630.
Baier, P.C., Schindehutte HJ., Thinane, K., Flugge G., Fuchs, E., Mansouri, A., Paulus, W., Gruss, P.,Trenwalder, C.(2004) Behavioral Changes in Unilaterally 6-Hydroxy-Dopamine Lesioned Rats after Transplantation of Differentiated Mouse Embryonic Stem Cells without Morphological Integration. Stem Cells 22, 396-404.
Lindvall O., Bjorklund, A. (2004) Cell Therapy in Parkinson's Disease. NeuroRx. 1, 382-393.
Zheng, X., Cai, J., Chen, J., Luo, Y., Zhi-Bing Y., Fotter, E., Wang, Y., Harvey, B., Miura, T., Backman, C., Chen, G-J., Rao, M.S., Freed. W.J. (2004) Dopaminergic Differentiation of Human Embryonic Stem Cells. Stem Cells 22, 925-940; Wilmut, I., Paterson, L.A. (2004) Stem cells and Cloning. Stem Cell Handbook ed. by Sell, S. 75-80.
Barker, R.A., Widner, H. (2004). Immune Problems in the Central Nervous System Cell Therapy. NeuroRx. 1, 472-481.