SLEEP

At last, you can put an end to the stress and annoyance of insomnia!

 

What would you do to feel good and get a better night’s sleep???????

Check this list below and see which applies to you:

I often have problems with falling asleep at the right time
I often find it painful to get up in the morning due to sleepiness
I am often awfully drowsy at school or at work
I regularly cut my sleep by 2-3 hours as compared with what my body seems to need
I use the alarm clock and truly hate it
I drink buckets of coffee or coke
I often take 2-4 hour naps in the evening
I just cant sleep

Difficulty falling or staying asleep is a common problem. About half of Americans report sleep difficulty at least occasionally, according to National Sleep Foundation surveys.

These woes - called insomnia by doctors - have far-reaching effects: a negative impact on concentration, productivity and mood. Most of us don't know much about sleep, not even our own and to make it worst ---- sleep problems have a profound effect on our sleeping and waking life.

Sleep a Brief introduction

Until the 1950s, most people thought of sleep as a passive, dormant part of our daily lives. We now know that our brains are very active during sleep. Moreover, sleep affects our daily functioning and our physical and mental health in many ways that we are just beginning to understand.

Nerve-signaling chemicals called neurotransmitters control whether we are asleep or awake by acting on different groups of nerve cells, or neurons, in the brain. Neurons in the brainstem, which connects the brain with the spinal cord, produce neurotransmitters such as serotonin and norepinephrine that keep some parts of the brain active while we are awake. Other neurons at the base of the brain begin signaling when we fall asleep. These neurons appear to "switch off" the signals that keep us awake. Research also suggests that a chemical called adenosine builds up in our blood while we are awake and causes drowsiness. This chemical gradually breaks down while we sleep.

During sleep, we usually pass through five phases of sleep: stages 1, 2, 3, 4, and REM (rapid eye movement) sleep. These stages progress in a cycle from stage 1 to REM sleep, then the cycle starts over again with stage 1 (see figure 1). We spend almost 50 percent of our total sleep time in stage 2 sleep, about 20 percent in REM sleep, and the remaining 30 percent in the other stages. Infants, by contrast, spend about half of their sleep time in REM sleep.

Sleep research is expanding and attracting more and more attention from scientists. Researchers now know that sleep is an active and dynamic state that greatly influences our waking hours, and they realize that we must understand sleep to fully understand the brain. Innovative techniques, such as brain imaging, can now help researchers understand how different brain regions function during sleep and how different activities and disorders affect sleep. Understanding the factors that affect sleep in health and disease also may lead to revolutionary new therapies for sleep disorders and to ways of overcoming jet lag and the problems associated with shift work. We can expect these and many other benefits from research that will allow us to truly understand sleep’s impact on our lives.

A Gallup poll showed that 52% per cent of the US population suffers, to some extent, from insomnia. Each year more than four billion sleeping pills are sold, but are pills the best insomnia cure?

The Stages of Sleep

The background activity of the brain is called the electroencephalogram (EEG) and can be recorded by the use of scalp electrodes. The dominant frequency and amplitude characteristic of the surface EEG varies with states of arousal.

A person goes through five stages while going to sleep.

Calm wakefulness is accompanied by alpha waves 8-12 Hz (cycles per second) and low voltage fast activity of mixed frequency. This is called stage one. Alpha waves disappear when we open our eyes.

As sleep deepens into stage two, bursts of 12-14 Hz (sleep spindles) and high amplitude slow waves appear.

The deep sleep of stages three and four is featured by an increasing proportion of high voltage slow activity. Breathing is regular in slow-wave sleep or non-REM (Rapid Eye Movements) sleep.

Delta activity (very slow waves, 0.5-4 Hz, high amplitude) is unusual in a normal record and accompanies deep sleep i.e. stages three and four sleep.

After about 70 minutes or so mostly spent in stages three and four, the first REM period occurs, usually heralded by an increase in body movements, and a shift in the EEG pattern from stage four to stage two. These rapid low-voltage irregular waves resemble those seen in alert humans; sleep, however, is not interrupted. This is called stage 5 or REM sleep, when the EEG activity gets desynchronised. There is marked muscle atonia despite the rapid eye movements in REM sleep, and the breathing is irregular.

Theta activity with a pattern of large regular waves occurs in normal children and is briefly seen in stage one sleep and also in REM sleep.

Non-REM (NREM) sleep passes through stages one and two, and spends 60-70 minutes in stages three and four. Sleep then lightens and a REM period follows. This cycle is repeated three or four times per night, at intervals of about 90 minutes throughout the night, depending on the length of sleep. REM sleep occupies 25% of total sleeping time.

What is the Scientific Method?
The word "science" is derived from a Latin verb meaning "to know." Scientists use the scientific method to construct an accurate representation of the world through the testing of scientific theories. These theories enhance our understanding and knowledge (to know) of the world. A theory, such as Einstein's theory of relativity or Darwin's theory of natural selection, accounts for many facts and attempts to explain a great variety of phenomena. Such a unifying theory does not become widely accepted in science unless its prediction can withstand thorough and continuous testing by experiments and observations (Campbell).

When the eyes are opened, the alpha rhythm is replaced by fast irregular low voltage activity with no dominant frequency, called the alpha block. Any form of sensory stimulation or mental concentration such as solving arithmetic problems could produce this break-up of the alpha rhythm. This replacement of the regular alpha rhythm with irregular low voltage activity is called “desynchronisation”.

 

Sleep Problems

At least 40 million Americans each year suffer from chronic, long-term sleep disorders each year, and an additional 20 million experience occasional sleeping problems. These disorders and the resulting sleep deprivation interfere with work, driving, and social activities. They also account for an estimated $16 billion in medical costs each year, while the indirect costs due to lost productivity and other factors are probably much greater. Doctors have described more than 70 sleep disorders, most of which can be managed effectively once they are correctly diagnosed. The most common sleep disorders include insomnia, sleep apnea, restless legs syndrome, and narcolepsy.

Your cause of insomnia could be attributed to a number of different sleep problems. Researchers are still learning about the functions of sleep, how we fall asleep, what happens while we sleep and how we wake up. Sleep will remain a mystery to science for many more years which is why there is no one-size-fits-all solution for every insomnia sleep problem.

Ascending circadian sleepiness: this means going to sleep at a time of day when you usually experience a rapid increase in drowsiness. Not earlier and not later! Knowing the timing of your circadian rhythm is perhaps critical for a good nights sleep.

Your Biological Rhythms

 

SLEEP PULSED ELECTROMAGNETIC FIELDS
AND SCIENTIFIC FINDINGS


OR WILL IT WORK

Pulsed electromagnetic therapy (PEMF) has been used with high degrees of success even where other therapies have failed, and without ANY meaningful adverse reactions, for decades world-wide. Numerous studies have been performed, all with acceptable degrees of success in controlling the problems associated with sleep.

One recent double-blind, placebo controlled study assessed the efficacy of impulse magnetic-field therapy for insomnia. One hundred patients were randomly assigned to either active treatment or placebo. Seventy percent of the patients given active treatment experienced substantial or even complete relief of their complaints; 24% reported clear improvement; 6% noted a slight improvement. This is simply incredible results!!!! (click here for study details)

Pulsed electromagnetic fields for sleep couldn't have come at a better time. Recent sleep research from literally every corner of the world has determined most people don't sleep well, as many as 10% are either diagnosed with or complain of chronic insomnia, and record numbers of young and old are turning to prescription sleep aids. Within the last few weeks it has been determined that even babies and toddlers are not sleeping as well as they used to.

Research conducted over previous years for pulsed electromagnetic field therapy indicates that varied improvements in neurological, physiological and psychological actions have been achieved with no adverse reactions. Pulsed electromagnetic field therapy has proven effective in thousands of cases where conventional therapy has failed

Do you think about the events of your day as you wind down for the evening? Do you worry about your family, your job, your finances, and what tomorrow will bring? Sometimes it's difficult to empty your mind of all these details long enough to fall asleep.
This can lead to tossing and turning as your mind fights sleep.

Sleep

Results of this double-blind, placebo-controlled study indicated that low-energy-emission therapy(PEMF) significantly improved sleeping patterns among patients suffering from chronic psychophysiological insomnia.

Therapy was administered 3 times per week, always in late afternoon and for 20 minutes, over a period of 4 weeks.

R. Hajdukovic, Effects of Low Energy Emission Therapy (LEET) on Sleep Structure,

First World Congress for Electricity and Magnetism in Biology and Medicine, 14-19June 1992, Lake Buena Vista, FL, p. 92.

This double-blind, placebo-controlled study examined the effects of low-energy emission therapy (27 MHz amplitude-modulated electromagnetic fields) in patients suffering from insomnia. Treatment consisted of 3 exposures per week over a 4-week period. Results showed significant increases in total sleep time among patients in the treatment group relative to controls.

M. Erman, Low-Energy Emission Therapy (LEET) Treatment for somnia,"

Bioelectromagnetics Society, 13th Annual Meeting, 23-27 June 1991, Salt Lake City, UT, p. 69.

This review article notes that studies have found low-energy emission therapy to be effective in the treatment of chronic insomnia, and suggests that it may also be of value for patients suffering from generalized anxiety disorders.

C. Guilleminault B. Pasche,Clinical Effects of Low Energy Emission Therapy,

Bioelectromagnetics Society, 15th Annual Meeting, 13-17 June 1993, Los Angeles, CA, p. 84.

"Is Sleep Deprivation Ruining Your Life?"

Sleep is the foundation of your life. Sleep deprivation affects every area of you life including your health, stamina, relationships, and even your career. The decisions you make and your ability to handle life's problems are dependent on the quality of your sleep.

Lack of sleep can lead to you being irritable and snappy. You may experience difficulty concentrating and get regular headaches. Your confidence and self-esteem can be ruined by sleep deprivation. Chronic sleep deprivation also appears to be the single biggest trigger for depression.

Turn any bed or lounge chair into a recuperation system for your body. Put it under your pillow-put it in your chair as you relax. That is it. It sounds easy– it is.

Not everyone will have the same results, and we cannot make any medical claims but the experience of our clients and the results of clinical studies on PEMF's(click here for study details) show amazing improvements from 70 to 90 percent of those involved.
.

LEARNING

Here are some Interesting characteristics of a person who is likely to be successful in learning:

highly optimistic
sleeps well
knowledge hungry
stress-tolerant
energetic but able to slow down at the time of learning

Here are some unfortunate characteristics that do not correlate well with the ability to study effectively

depressive
problems with sleep (esp. insomnia)
high levels of stress
overexcited
low stress tolerance (smokers, people with a drinking problem, abusers of mood altering substances, etc.)

It has been known since the 1920s that sleep improves recall in learning. However, only recently, research by Dr Robert Stickgold, assistant professor of psychiatry at Massachusetts Mental Health Center, has made international headlines. Dr Stickgold demonstrated a fact that has long been known yet little appreciated: sleep is necessary for learning! Without sleep we reduce the retention of facts we have learned the previous day (and not only). Studying nights before an exam may be sufficient for passing the exam, yet it will leave few useful traces in long-term memory. The exam on its own replaces knowledge as the main purpose of studying!

 

The Effects Of Sleep Deprivation

A growing number of scientists are discovering that the sleeping brain does something to solidify memories and process newly learned information. With most people routinely getting far less sleep than they should, some experts are starting to wonder if widespread sleep deprivation is having a real but unrecognised effect on society's brainpower and creativity.

Recent research is revealing that sleep is essential not only to brain function but to the proper function of every bodily organ.

Sleep researchers can point to a whole list of problems and diseases connected to sleep deprivation. A 19-year-old college student with a diagnosis of bipolar disorder (manic-depression) has too much energy to sleep for six nights running and experiences uncontrolled mania.

Not Everyone who has insomnia is kept awake by worries and problems. Every insomniac is not trying to punish him or herself. There are many other things that can cause insomnia.

But, there is Perhaps one common denominator in all insomnia; there is one factor that is always present.

This big factor is fear of not being able to go to sleep.

A 67-year-old man with prostate problems wakes up to go to the bathroom half a dozen times a night, and one morning he has a heart attack. A healthy man of 30 gets half his required sleep - fours hours a night - for a week and ends up in a pre-diabetic state with the metabolism of his grandfather.

An 82-year-old woman falls and breaks her hip, maybe for the same reason that a 43-year-old truck driver slams into a barrier at 3a.m. - inattention and slowed response because of partial sleep deprivation.

The need for sleep is so strong that without enough of it, people can't even muster enough willpower to stay awake to save their lives. Sleep deprivation can come with a high cost.

The message is clear: get your sleep or suffer the consequences.
Dr David Tracy

MEDITATION

Meditating does more than just feel good and calm you down, it makes you perform better – and alters the structure of your brain, researchers have found.

People who meditate say the practice restores their energy, and some claim they need less sleep as a result. Many studies have reported that the brain works differently during meditation – brainwave patterns change and neuronal firing patterns synchronise. But whether meditation actually brings any of the restorative benefits of sleep has remained largely unexplored.

So Bruce O’Hara and colleagues at the University of Kentucky in Lexington, US, decided to investigate. They used a well-established “psychomotor vigilance task”, which has long been used to quantify the effects of sleepiness on mental acuity. The test involves staring at an LCD screen and pressing a button as soon as an image pops up. Typically, people take 200 to 300 milliseconds to respond, but sleep-deprived people take much longer, and sometimes miss the stimulus altogether.

Ten volunteers were tested before and after 40 minutes of either sleep, meditation, reading or light conversation, with all subjects trying all conditions. The 40-minute nap was known to improve performance (after an hour or so to recover from grogginess). But what astonished the researchers was that meditation was the only intervention that immediately led to superior performance, despite none of the volunteers being experienced at meditation.

“Every single subject showed improvement,” says O’Hara. The improvement was even more dramatic after a night without sleep. But, he admits: “Why it improves performance, we do not know.” The team is now studying experienced meditators, who spend several hours each day in practice.

Brain builder
What effect meditating has on the structure of the brain has also been a matter of some debate. Now Sara Lazar at the Massachusetts General Hospital in Boston, US, and colleagues have used MRI to compare 15 meditators, with experience ranging from 1 to 30 years, and 15 non-meditators.

They found that meditating actually increases the thickness of the cortex in areas involved in attention and sensory processing, such as the prefrontal cortex and the right anterior insula.

“You are exercising it while you meditate, and it gets bigger,” she says. The finding is in line with studies showing that accomplished musicians, athletes and linguists all have thickening in relevant areas of the cortex. It is further evidence, says Lazar, that yogis “aren’t just sitting there doing nothing".

The growth of the cortex is not due to the growth of new neurons, she points out, but results from wider blood vessels, more supporting structures such as glia and astrocytes, and increased branching and connections.

The new studies were presented at the Society for Neuroscience annual meeting, in Washington DC, US
11:01 15 November 2005
NewScientist.com news service
Alison Motluk

The single most important activity of your life is to sleep

Turn any bed or lounge chair into a recuperation system for your body.
Feel deep states of meditation,
Put it under your pillow-put it in your chair as you relax. That is it. It sounds easy– it is
.

 

MORE SCIENTIFIC INFO

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2004 Apr;21(2):219-24. Related Articles, Links [Study on the influence of simulative EEG modulation magnetic field on the discharge of median raphe nuclei]

 

Wang M, Li Y, Wang X, Guo M.

College of Precision Instrument and Opto-electronics Engineering, Tianjin University, Tianjin 300072, China.

In this paper the response characteristic of the nerve fiber to the modulation magnetic field induction is studied by using the method of numeric simulation. It is found that the nerve fiber is sensitive to the low frequency modulated signal but not to the high frequency carrier wave. A simulative EEG signal generator is developed according to the change of EEG rhythm during the sleep. The simulative EEG square wave is modulated by high-frequency magnetic impulse. The modulation magnetic field is coupled into the rabbit's brain to study the influence of magnetic stimulation on the discharge of 5-hydroxytryptamine (5-HT) nerve cell. The experiment results demonstrate that discharge frequency of median raphe nuclei related to sleep changes significantly and the discharge becomes slow, which shows that magnetic stimulation can inhibit electrical activity of 5-HT nerve cell and provide a new way to improve insomnia.

PMID: 15143544 [PubMed - indexed for MEDLINE]

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Sleep. 1996 May;19(4):327-36.


Effects of low energy emission therapy in chronic psychophysiological insomnia.

Pasche B, Erman M, Hayduk R, Mitler MM, Reite M, Higgs L, Kuster N, Rossel C, Dafni U, Amato D, Barbault A, Lebet JP.

Symtonic USA, Inc., New York, New York 10162, USA.

The treatment of chronic psychophysiological insomnia presents a challenge that has not been met using currently available pharmacotherapy. Low energy emission therapy (LEET) has been developed as a potential alternative therapy for this disorder. LEET consists of amplitude-modulated electromagnetic fields delivered intrabuccally by means of an electrically conducting mouthpiece in direct contact with the oral mucosa. The effect of LEET on chronic psychophysiological insomnia was assessed with polysomnography (PSG) and sleep rating forms on a total of 106 patients at two different centers. Active or inactive LEET was administered for 20 minutes in late afternoon three times a week for a total of 12 treatments. Primary efficacy endpoints evaluating the results were changes from baseline in PSG-assessed total sleep time (TST) and sleep latency (SL). Secondary endpoints were changes in sleep efficiency (SE), sleep stages, and reports by the subjects of SL and TST. There was a significant increase in TST as assessed by PSG between baseline and post-treatment values for the active treatment group (76.0 +/- 11.1 minutes, p = 0.0001). The increase for the inactive treatment group was not statistically significant. The TST improvement was significantly greater for the active group when compared to the inactive group (adjusted for baseline TST; p = 0.020. R1 = 0.20). There was a significant decrease in SL as assessed by PSG between baseline and post-treatment values for the active treatment group (-21.6 +/- 5.9 minutes, p = 0.0006), whereas the decrease noted for the inactive treatment group was not statistically significant. The difference in SL decrease between the two treatment groups was marginally significant (adjusted for baseline SL and center, p = 0.068, R2 = 0.60). The number of sleep cycles per night increased by 30% after active treatment (p = 0.0001) but was unchanged following inactive treatment. Subjects did not experience rebound insomnia, and there were no significant side effects. The data presented in this report indicate that LEET administered for 20 minutes three times a week increased TST and reduced SL in chronic psychophysiological insomnia. LEET is safe and well tolerated and it effectively improved the sleep of chronic insomniacs given 12 treatments over a 4-week period by increasing the number of sleep cycles without altering the percentage of the various sleep stages during the night. The therapeutic action of LEET differs from that of currently available drug therapies in that the sleep pattern noted in insomniacs following LEET treatment more closely resembles nocturnal physiological sleep. This novel treatment may offer an attractive alternative therapy for chronic insomnia.

PMID: 8776791 [PubMed - indexed for MEDLINE]

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Bioelectromagnetics. 1994;15(1):67-75.


Sleep inducing effect of low energy emission therapy.

Reite M, Higgs L, Lebet JP, Barbault A, Rossel C, Kuster N, Dafni U, Amato D, Pasche B.

Department of Psychiatry, University of Colorado Health Sciences Center, Denver.

The sleep inducing effect of a 15 min treatment with either an active or an inactive Low Energy Emission Therapy (LEET) device emitting amplitude-modulated electromagnetic (EM) fields was investigated in a double-blind cross-over study performed on 52 healthy subjects. All subjects were exposed to both active and inactive LEET treatment sessions, with an interval of at least 1 week between the two sessions. LEET consists of 27.12 MHz amplitude-modulated (sine wave) EM fields emitted intrabuccally by means of an electrically conducting mouthpiece in direct contact with the oral mucosa. The estimated local peak SAR is less than 10 W/kg in the oral mucosa and 0.1 to 100 mW/kg in brain tissue. No appreciable sensation is experienced during treatment, and subjects are therefore unable to tell whether they are receiving an active or an inactive treatment. In this study the active treatment consisted of EM fields intermittently amplitude-modulated (sine wave) at 42.7 Hz for 3 s followed by a pause of 1 s during which no EM fields were emitted. During the inactive treatment no EM fields were emitted. Baseline EEGs were obtained and 15 min post-treatment EEGs were recorded and analyzed according to the Loomis classification. A significant decrease (paired t test) in sleep latency to stage B2 (-1.78 +/- 5.57 min, P = 0.013), and an increase in the total duration of stage B2 (1.15 +/- 2.47 min, P = 0.0008) were observed on active treatment as compared with inactive treatment.(ABSTRACT TRUNCATED AT 250 WORDS)

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 8155071 [PubMed - indexed for MEDLINE]

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Med Pr. 1983;34(1):65-73. Related Articles, Links


[Health status of the workers exposed to strong, constant magnetic fields]

[Article in Polish]

Lankosz J, Tokarz J, Weselucha P, Ochmanski W, Gzyl E, Barbaro B, Gatarski J, Drozdzewicz L, Kielar I.

Forty two workers underwent examinations under clinical conditions. The workers were affected by the magnetic field of intensities ranging between 112-190 Gauss, depending on the workplace. They underwent internal, ophthalmological, psychological, psychiatric and analytical examinations and the health status of those exposed was compared to that of twenty controls. Most subjects, mainly those of long length of employment in e-m fields exposure, exhibited nonspecific abdominal pains, general weakness, insomnia, increased thirst and conjunctivitis.

PMID: 6865739 [PubMed - indexed for MEDLINE]

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Entrez-PubMed is a search and retrieval system that integrates information from databases at U.S. National Center of Biotechnology Information; the National Library of Medicine and the National Institutes of Health.


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Dtsch Med Wochenschr 2002 Apr 19;127(16):872
Sleep disorders caused by electrosmog?
Schweisfurth H.
Klinikum, Thiemstrasse 111, 03048 Cottbus.
Adv Ther. 2001 Jul-Aug;18(4):174-80.
Impulse magnetic-field therapy for insomnia: a double-blind, placebo-controlled study.
Pelka RB, Jaenicke C, Gruenwald J.
Universitat der Bundeswehr Munchen Neubiberg/Munich, Germany.
70% (n = 34) of the patients given active treatment experienced substantial or even complete relief of their complaints; 24% (n = 12) reported clear improvement; 6% (n = 3) noted a slight improvement.

J Neuropsychiatry Clin Neurosci. 2002 Summer;14(3):270-6.
Repetitive transcranial magnetic stimulation treatment of comorbid posttraumatic stress disorder and major depression.
Rosenberg PB, Mehndiratta RB, Mehndiratta YP, Wamer A, Rosse RB, Balish M.
Mental Health Service Line, Department of Veterans Affairs Medical Center, Washington, DC 20422, USA.
Seventy-five percent of the patients had a clinically significant antidepressant response after rTMS, and 50% had sustained response at 2-month follow-up. Comparable improvements were seen in anxiety, hostility, and insomnia, but only minimal improvement in PTSD symptoms. Left frontal cortical rTMS may have promise for treating depression in PTSD, but there may be a dissociation between treating mood and treating core PTSD symptoms.
about 100 tms/rtms studies at rTMS/TMS

Crit Rev Biomed Eng. 2001;29(1):125-33
Investigation of brain potentials in sleeping humans exposed to the electromagnetic field of mobile phones.
Lebedeva NN, Sulimov AV, Sulimova OP, Korotkovskaya TI, Gailus T.
Institute of Higher Nerve Activity and Neurophysiology, Russian Academy of Sciences.

Clin Neurophysiol. 2000 Nov;111(11):1936-41.
Nocturnal magnetic field exposure: gender-specific effects on heart rate variability and sleep.
Graham C, Sastre A, Cook MR, Gerkovich MM.
Midwest Research Institute, 425 Volker Boulevard, Kansas City, MO 64110, USA.

Med Hypotheses 2000 Apr;54(4):630-3
The effects of natural and man-made electromagnetic fields on mood and behavior: the role of sleep disturbances.
Sher L.
The author further suggests that the development of sleep abnormalities in persons exposed to artificial electromagnetic fields may predict the onset of a psychiatric disorder at a later time and that early intervention may prevent the onset of a psychiatric disease.

J Sleep Res. 1999 Mar;8(1):77-81.
A 50-Hz electromagnetic field impairs sleep.
Akerstedt T, Arnetz B, Ficca G, Paulsson LE, Kallner A.
National Institute for Psychosocial Factors and Health, Karolinska Institute, Stockholm, Sweden.

Int J Neurosci. 1991 Aug;59(4):259-62.
Age-related disruption of circadian rhythms: possible relationship to memory impairment and implications for therapy with magnetic fields.
Sandyk R, Anninos PA, Tsagas N.
Department of Psychiatry, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY 10461.

Sleep. 1996 May;19(4):327-36.
Effects of low energy emission therapy in chronic psychophysiological insomnia.

Pasche B, Erman M, Hayduk R, Mitler MM, Reite M, Higgs L, Kuster N, Rossel C, Dafni U, Amato D, Barbault A, Lebet JP.
The number of sleep cycles per night increased by 30% after active treatment (p = 0.0001) but was unchanged following inactive treatment. Subjects did not experience rebound insomnia, and there were no significant side effects. The data presented in this report indicate that LEET administered for 20 minutes three times a week increased TST and reduced SL in chronic psychophysiological insomnia. LEET is safe and well tolerated and it effectively improved the sleep of chronic insomniacs given 12 treatments over a 4-week period by increasing the number of sleep cycles without altering the percentage of the various sleep stages during the night. The therapeutic action of LEET differs from that of currently available drug therapies in that the sleep pattern noted in insomniacs following LEET treatment more closely resembles nocturnal physiological sleep. This novel treatment may offer an attractive alternative therapy for chronic insomnia.
------------------------------------------------------------------------
Bioelectromagnetics. 1994;15(1):67-75. Related Articles, Links
Sleep inducing effect of low energy emission therapy.
Reite M, Higgs L, Lebet JP, Barbault A, Rossel C, Kuster N, Dafni U, Amato D, Pasche B.
Department of Psychiatry, University of Colorado Health Sciences Center, Denver.
The sleep inducing effect of a 15 min treatment with either an active or an inactive Low Energy Emission Therapy (LEET) device emitting amplitude-modulated electromagnetic (EM) fields was investigated in a double-blind cross-over study performed on 52 healthy subjects. A significant decrease (paired t test) in sleep latency to stage B2 (-1.78 +/- 5.57 min, P = 0.013), and an increase in the total duration of stage B2 (1.15 +/- 2.47 min, P = 0.0008) were observed on active treatment as compared with inactive treatment.
------------------------------------------------------------------------
Med Pr. 1983;34(1):65-73.
[Health status of the workers exposed to strong, constant magnetic fields]
[Article in Polish]
Lankosz J, Tokarz J, Weselucha P, Ochmanski W, Gzyl E, Barbaro B, Gatarski J, Drozdzewicz L, Kielar I.
Forty two workers underwent examinations under clinical conditions. Most subjects, mainly those of long length of employment in e-m fields exposure, exhibited nonspecific abdominal pains, general weakness, insomnia, increased thirst and conjunctivitis.
PMID: 6865739 [PubMed - indexed for MEDLINE]
------------------------------------------------------------------------
Cesk Neurol Neurochir. 1976 Jan;39(1):1-11. Related Articles, Links
[Use of magnetic fields and electronic noise in the treatment of insomnia and neurosis]
[Article in Czech]
Grunner O.
PMID: 1082800 [PubMed - indexed for MEDLINE]
------------------------------------------------------------------------
Arch Mal Prof. 1971 Oct-Nov;32(10):679-83. Related Articles, Links
[Study of biological disturbances in O.R.T.F. technicians in some high-frequency electromagnetic fields]
[Article in French]
Deroche M.
PMID: 5290081

Wang M, Li Y, Wang X, Guo M. Related Articles, Links
[Study on the influence of simulative EEG modulation magnetic field on the discharge of median raphe nuclei]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2004 Apr;21(2):219-24. Chinese.
PMID: 15143544 [PubMed - indexed for MEDLINE]

2: Jouvet M. Related Articles, Links
Sleep and serotonin: an unfinished story.
Neuropsychopharmacology. 1999 Aug;21(2 Suppl):24S-27S. Review.
PMID: 10432485 [PubMed - indexed for MEDLINE]

3: Ootsuka Y, Blessing WW. Related Articles, Links
Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit.
Am J Physiol Regul Integr Comp Physiol. 2005 Apr;288(4):R909-18. Epub 2004 Nov 18.
PMID: 15550616 [PubMed - indexed for MEDLINE]

4: Puizillout JJ, Gaudin-Chazal G, Sayadi A, Vigier D. Related Articles, Links
Serotoninergic mechanisms and sleep.
J Physiol (Paris). 1981;77(2-3):415-24. Review.
PMID: 6457142 [PubMed - indexed for MEDLINE]

5: Puizillout JJ, Gaudin-Chazal G, Daszuta A, Seyfritz N, Ternaux JP. Related Articles, Links
Release of endogenous serotonin from "encephale isole" cats. II - Correlations with raphe neuronal activity and sleep and wakefulness.
J Physiol (Paris). 1979;75(5):531-7.
PMID: 533869 [PubMed - indexed for MEDLINE]

6: Khanbabian MV, Kirakosian MP, Sarkisian RSh, Gevorkian AP. Related Articles, Links
[Influence of the medial raphe nucleus damage on discharge activity of the central and bazolateral nuclei of the amygdala]
Zh Vyssh Nerv Deiat Im I P Pavlova. 2004 Sep-Oct;54(5):698-704. Russian.
PMID: 15573707 [PubMed - indexed for MEDLINE]

7: Foo H, Mason P. Related Articles, Links
Brainstem modulation of pain during sleep and waking.
Sleep Med Rev. 2003 Apr;7(2):145-54. Review.
PMID: 12628215 [PubMed - indexed for MEDLINE]

8: Kloiber O, Okada Y, Hossmann KA. Related Articles, Links
[A 4.7 T static magnetic field has no effect on the electric activity of the brain in cats]
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1990 Dec;21(4):229-32. German.
PMID: 2127012 [PubMed - indexed for MEDLINE]

9: Petrova EV, Guliaeva NV, Titarov SI, Rozhnov IuV, Koval'zon VM. Related Articles, Links
[Effect of impulse extrabroad-band electromagnetic radiation on electroencephalogram and sleep in laboratory animals]
Ross Fiziol Zh Im I M Sechenova. 2003 Jul;89(7):786-94. Russian.
PMID: 14758614 [PubMed - indexed for MEDLINE]

10: Chu YX, Liu J, Feng J, Wang Y, Zhang QJ, Li Q. Related Articles, Links
[Changes of discharge rate and pattern of 5-hydroxytrypamine neurons of dorsal raphe nucleus in a rat model of Parkinson's disease]
Sheng Li Xue Bao. 2004 Oct 25;56(5):597-602. Chinese.
PMID: 15497040 [PubMed - indexed for MEDLINE]

11: Fujita Y, Sato H, Takeuchi T, Minami S. Related Articles, Links
Median raphe- and contralateral hippocampus-elicited EEG spikes which correspond to hyperpolarizations of pyramidal cells in the kindled hippocampus of the rabbit.
Brain Res. 1983 Nov 14;278(1-2):313-7.
PMID: 6640323 [PubMed - indexed for MEDLINE]

12: Ursin R. Related Articles, Links
Serotonin and sleep.
Sleep Med Rev. 2002 Feb;6(1):55-69. Review.
PMID: 12531142 [PubMed - indexed for MEDLINE]

13: Bell G, Marino A, Chesson A, Struve F. Related Articles, Links
Electrical states in the rabbit brain can be altered by light and electromagnetic fields.
Brain Res. 1992 Jan 20;570(1-2):307-15.
PMID: 1617421 [PubMed - indexed for MEDLINE]

14: Guilleminault C, Baker TL. Related Articles, Links
Sleep and electroencephalography: points of interest and points of controversy.
J Clin Neurophysiol. 1984 Jul;1(3):275-91. Review. No abstract available.
PMID: 6399910 [PubMed - indexed for MEDLINE]

15: Adrien J. Related Articles, Links
[Development of slow wave sleep after lesion of the anterior Raphe nuclei of the newborn rat]
C R Acad Sci Hebd Seances Acad Sci D. 1975 Apr 14;280(14):1725-7. French.
PMID: 807367 [PubMed - indexed for MEDLINE]

16: Adrien J. Related Articles, Links
[Sleep organisation in the kitten following early lesions to the structures involved in the regulation of alertness (author's transl)]
Rev Electroencephalogr Neurophysiol Clin. 1977 Jul-Sep;7(3):278-83. French.
PMID: 563095 [PubMed - indexed for MEDLINE]

17: Harsing LG Jr, Prauda I, Barkoczy J, Matyus P, Juranyi Z. Related Articles, Links
A 5-HT7 heteroreceptor-mediated inhibition of [3H]serotonin release in raphe nuclei slices of the rat: evidence for a serotonergic-glutamatergic interaction.
Neurochem Res. 2004 Aug;29(8):1487-97.
PMID: 15260125 [PubMed - indexed for MEDLINE]

18: Kramarenko AV, Tan U. Related Articles, Links
Effects of high-frequency electromagnetic fields on human EEG: a brain mapping study.
Int J Neurosci. 2003 Jul;113(7):1007-19.
PMID: 12881192 [PubMed - indexed for MEDLINE]

19: Kuo TB, Yang CC. Related Articles, Links
Scatterplot analysis of EEG slow-wave magnitude and heart rate variability: an integrative exploration of cerebral cortical and autonomic functions.
Sleep. 2004 Jun 15;27(4):648-56.
PMID: 15282999 [PubMed - indexed for MEDLINE]

20: Durka PJ, Szelenberger W, Blinowska KJ, Androsiuk W, Myszka M. Related Articles, Links
Adaptive time-frequency parametrization in pharmaco EEG.
J Neurosci Methods. 2002 May 30;117(1):65-71.
PMID: 12084565 [PubMed - indexed for MEDLINE]