Effects of Cerebral Electrical Stimulation on Alcoholism: A Pilot Study
This research was supported by a grant of the Entente auxiliaire Canada/Québec sur le dévelopment scientifique et technologique, Ministry of Science and Technology, Canada, Ministy of Commerce, and N-S Inc., Montreal. The support of Douglas Hospital Research Centre is also acknowledged.
Copyright 1995 The Research Society on Alcoholism
Claims of biological effectiveness (neurochemical, hormonal and EEG changes, naloxone-reversible analgesia in rats, etc.) and of clinical effectiveness (anxiety, depression, cognitive functions in alcoholics) have often relied on poorly controlled data. A recent controlled study in the treatment of opiate withdrawal has been positive. The present double-blind controlled study compares active CES with sham stimulation in 64 alcohol-dependent males. Over 4 weeks, both treatment groups improved significantly in most aspects. In the active treatment group additional significant improvement was observed in week-end alcohol consumption, and in two psychological measures: depression and stress symptoms index, but not in general drinking behavior.