Action Increase adrenal testosterone and oestradiol production.
Maintains sexual arousal.
Orally, cnidium extract(10% Osthol) is used for increasing sexual performance
and libido, erectile dysfunction, infertility, body building, increasing energy,
cancer, osteoporosis, and fungal and bacterial infections.
Stimulates the pituitary and adrenal glands
Indications Adrenal exhaustion effecting sexual function.
Low libido sexual disinterest.
Increased sexual stamina and performance.
Male and female sexual disorders, including erectile dysfunction, premature
ejaculation,orgasmic disorder, and hypoactive sexual desire, low libido, inability
to maintain erection. Impotence and sexual disinterest.
Sterility.
Chronic nephritis, adrenal exhaustion leading to low libido.
Listlessness and 'lack of spirit', Aching and weakness of lower back and or
knees. Weakness of the legs and lumbar region.
Endocrine Tonic Restorative to the reproductive systems function X)ES can be
used in cases of low libido, sexual disinterest or for increased sexual stamina
and performance. Also useful for building lean muscle, increasing HDL and restoring
endocrine function.
Major therapeutic action
in TCM warming the kidney and Strengthens Yang, Tonifies jing, Qi and Blood.
Contradiction Damp Heat, BPH, "Youth"
Note Can cause emotional irrritability due to Liver Qi constraint in those
susceptible.
Research 1) Ren Shen can regulate nervous function and restore dysfunctional
nervous progress caused by tension and then improve memory and to focus. It
has anti-fatigue effects which helps improve working and functional ability.
Ren Shen can dilate coronary arteries, cerebral blood vessels, ocular blood
vessels and peripheral blood vessels of the whole organism, while contracting
isolated auricular blood vessels of rabbits and isolated blood vessels of rats.
Extract of Ren Shen can increase RBC, Hb and WBC of rabbits. Ginsenosides can
increase content of ACTH and corticosteroid in plasma by exciting hypothalamic
or pituitary function, it has gonadotropic effects. Ginsenosides can also promote
metabolism of lipids and biologic synthesis of cholesterol and blood lipoprotein
of rats. But both Ren Shen and ginsenosides can decrease hypercholesterolemia
in animals. Besides, Ren Shen can reinforce phagocytic function of WBC and
reticuloendothelial system. It also has diuretic, anti-shock and anti-tumor
actions.
2) Lu Rong can boost strength and endurance, increase oxygen-carrying capacity
of the blood, stimulate production and circulation of blood, increase blood
count, and lower the level of free radicals. As an aphrodisiac, Lu Rong can
treat sexual dysfunction, boost estrogen and testosterone levels. It can promote
youthfulness, increase mental clarity, improve immune system functioning, and
promote rapid recovery from illness. It also has anticancer and anti-inflammatory
effects.3) Xian Ling Pi has hormone-like effects. It can decrease blood pressure
and increase blood flow in coronary artery. 100% decoction of this herb can
decrease lipoprotein, cholesterol and blood sugar. It also can improve and
enhance physical stamina and immunity.
4) Dang Gui has bi-directional functions on the uterus: it can inhibit the
uterine muscle with its volatile oil, and excite the uterus muscle with its
water-soluble and alcohol-soluble nonvolatile substance. Dang Gui can dilate
coronary arteries in isolated guinea pigs, and has been shown to increase blood
flow and lower the blood pressure in clinical trials. It can decrease blood
fat of experimental hyperlipoidemia and has a protective effect on experimental
atheroma. Dang Gui and its ingredient ferulic acid can inhibit palate aggregation
and antagonize formation of thrombosis. It also has anti-anemia, sedative,
analgesic, anti-inflammatory and antibacterial effects. Besides, Dang Gui can
promote the transformation of lymphocytes.5) Fructus Cnidii is traditionally
regarded as medicine of warming the kidney to activate YANG. Modern research
proved that it has certain effects on animals with deficient Yang, which may
be gained by acting on metabolism of cyclic nucleoside acid and prostaglandin.
Coumarin/Osthole may be effective ingredient of Fructus Cnidii for warming
the kidney to activate YANG. There is one specific prostaglandin that indeed
plays a role in the male sexual tract, prostaglandin E1.In the words of medical
researcher A.Lea:" prostaglandin E1 is a vasodilating agent which acts
by relaxing the smooth muscles of the corpus cavemosum and by increasing the
diameter of cavemous arteries; this leads to erection."
6) Cnidii extract contains Osthole 10%, Coumarines 1%
Osthole is a libido stimulator: researchers investigated the cavemosal relaxant
effect of osthole, which has been long used in China as an herbal medicine
to improve both male and female sexual dysfunction. The data suggested that
osthole possessesa relaxant effect on rabbit corpus cavernosal tissues which
is attributatble to the release of NO from sinusoidal endothelium and to the
potentiation of the cGMP and/or cAMP signal mediating relaxation of cavernosal
smooth muscle by inhibiting phosphodiesterase." (Corpus cavernosum = one
of the columns of erectile tissue forming the dorsum of the penis (one of the
two columns of erectile tissue forming the clitoris)).
Osthole Osthola, osthol, Osthol,osthenol, Ost, Cnidiadin, (C15H16O3), Coumarin,
7-methoxy-8-(3-methyl-2-butenyl); 2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl);
7-Methoxy-8-(3-methyl-2-butenyl)-coumarin; 7-Methoxy-8-isopentenylcoumarin;
osthol; osthole; Ostol; Ostole
